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Two Big Ten contenders will meet on Thursday, Feb. 26 when the No. 13 Michigan State Spartans head to West Lafayette to battle the No. 8 Purdue Boilermakers. The Spartans have won two in a row entering this matchup, but are just 3-3 in their last six games as they try to re-establish some momentum ahead of the postseason. Purdue bounced back from a loss to Michigan with a 29-point win over Indiana, and has won five of its last six games. This is the lone meeting between these teams in the regular season.

We'll look at the best bets for Michigan State vs. Purdue on Thursday, using odds from DraftKings Sportsbook and recommendations from the SportsLine Projection Model. It simulates every college basketball game 10,000 times and entered Week 17 on a sizzling 11-1 run on its top-rated Over/Under college basketball picks dating back to last season, and is on a 20-11 run on top-rated CBB side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.

Bet on Michigan State vs. Purdue at DraftKings, where new users get $200 if their first bet of $5+ wins:

Michigan State vs. Purdue model picks for Feb. 26

Michigan State +7.5

This line has actually moved up from 6.5 to 7.5, and the SportsLine model has the Spartans covering in 52% of simulations. Even though Purdue has been on a roll lately, only one of its three wins by double digits came at home. Purdue is 5-9 ATS on the season as a home favorite and while Michigan State is just 2-4-1 ATS on the road, the model is backing Tom Izzo's bunch to keep this game close.

Michigan State money line

The Spartans only win in 30% of model simulations, but that's offering enough value at +260 odds. Michigan State has not been good on the road this season though, going 4-3 away from East Lansing. On the flip side, Purdue is 12-3 straight up at Mackey Arena. 

Over 142.5

This is the model's strongest recommendation, with the Over hitting in 71.3% of simulations for a "B" grade play. The Boilermakers have gone Over their totals in three of their last four games and four of their last six. They are 10-5 to the Over at home. The Spartans had six straight Overs before finally hitting an Under in their last contest. They are 11-16 overall to the Over on the season but 4-3 to the Over in road games.