The 2024 Players Era Thanksgiving Festival begins on Tuesday with eight teams battling it out for money that will go into their NIL collectives and the action begins with the San Diego State Aztecs taking on the Creighton Bluejays. San Diego State went to the Sweet 16 and was 2-1 last season while Creighton is coming off of a Sweet 16 run of its own and is ranked 21st in the AP Top 25 after a 4-1 start. These programs met in the Elite Eight just two seasons ago, with SDSU capturing a 57-56 win to make the Final Four as 2.5-point underdogs in that contest.

Tipoff is scheduled for 2 p.m. ET at MGM Grand Garden Arena in Las Vegas. The Bluejays are 4.5-point favorites in the latest Creighton vs. San Diego State odds from SportsLine consensus, while the over/under for total points scored is 138.5. Before entering any San Diego State vs. Creighton picks, you need to see the college basketball predictions and betting advice from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 4 of the 2024-25 season on a 162-118 betting roll (+1952) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps has seen huge returns.

Now, the model has dialed in on Creighton vs. San Diego State and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college basketball betting lines and trends for SDSU vs. Creighton:

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  • Creighton vs. San Diego State spread: Creighton -4.5
  • Creighton vs. San Diego State over/under: 138.5 points 
  • Creighton vs. San Diego State money line: Creighton -191, SDSU +159
  • Creighton vs. San Diego State picks: See picks here

Why Creighton can cover

The Bluejays began their season with four dominant wins over lesser opponents but stumbled at home against Nebraska on Friday. Pop Isaacs led all scorers with 25 points in the 74-63 loss and the Texas Tech transfer is averaging 13.5 points and 6.0 rebounds per game in his first season at Creighton.

It was a strange game for national player of the year candidate Ryan Kalkbrenner, who only attempted one shot from the field despite playing 39 minutes. Kalkbrenner is still averaging 21.3 points and 9.0 rebounds per game on the season and he'll almost certainly be more involved offensively against SDSU. See who to back at SportsLine

Why SDSU can cover

Meanwhile, San Diego State should be well rested after playing a light schedule early in the season. The Aztecs haven't played since a Nov. 18 loss to Gonzaga (80-67). They also haven't played a game with fewer than five days rest all season, which should bode well with three games coming this week.

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Brian Dutcher's squad has four players averaging double-figures in scoring and FAU transfer Nick Boyd leads the way with 14.7 ppg. This will be the sixth meeting between these programs and Creighton head coach Greg McDermott has been on the opposing sideline for all five previous matchups. SDSU is 3-2 straight up and against the spread in those head-to-heads. See who to back at SportsLine

How to make Creighton vs. San Diego State picks

SportsLine's model is leaning Over on the total, predicting the teams combine for 144 points. It also says one side of the spread hits in over 60% of simulations. You can see the model's pick at SportsLine.

So who wins Creighton vs. San Diego State, and which side of the spread hits over 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out.

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