The Virginia Cavaliers will take on the Memphis Tigers in a holiday battle at 7 p.m. ET on Wednesday at John Paul Jones Arena. Virginia is 6-4 overall and 5-0 at home, while Memphis is 8-2 overall and 2-0 on the road. The Tigers are 7-3 against the spread this season, while the Cavaliers are 3-7 against the spread in 2024. 

Memphis is favored by 4 points in the latest Virginia vs. Memphis odds via SportsLine consensus, and the over/under is 129.5 points. Before entering any Memphis vs. Virginia picks, you'll want to see the college basketball predictions from the advanced computer model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 7 of the 2024-25 season on a 176-128 betting roll (+2066) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps has seen huge returns.

Now, the model has set its sights on Memphis vs. Virginia. You can head to SportsLine to see its picks. Here are several college basketball betting lines for the game:

  • Virginia vs. Memphis spread: Virginia +4
  • Virginia vs. Memphis over/under: 129.5 points
  • Virginia vs. Memphis money line: Virginia: +155, Memphis: -187
  • Virginia vs. Memphis picks: See picks here
  • Virginia vs. Memphis streaming: FuboTV (Try for free)

Why Virginia can cover

Virginia took a loss when the Cavaliers played away from home last Saturday, but their home fans gave them all the motivation they needed on Thursday. The Cavaliers took down Bethune-Cook, 59-41, on their home floor.

Multiple players turned in solid performances to lead Virginia to victory, but perhaps none more so than Jacob Cofie, who dropped a double-double with 12 points and 10 rebounds. The team also got some help courtesy of Ishan Sharma, who recorded 12 points, five rebounds and three assists. The Cavaliers have won six consecutive games at home and are 9-1 in their last 10 games played on a Wednesday. See which team to pick here

Why Memphis can cover 

Meanwhile, it may have taken overtime to finish the job, but Memphis ultimately got the result the Tigers hoped for on Saturday. They came out on top against Clemson by a score of 87-82. Memphis' success was the result of a balanced attack that saw several players step up, but Tyrese Hunter led the charge by going 7 for 11 from beyond the arc en route to 23 points. 

Another player making a difference was Colby Rogers, who went 9 for 14 en route to 22 points. For the season, Rogers is averaging 13.4 points, 1.8 rebounds and 1.4 assists per game. He's knocking down 45.3% of his field goals and 44.6% of his 3-point attempts. See which team to pick here

How to make Virginia vs. Memphis picks

The model has simulated Virginia vs. Memphis 10,000 times and the results are in. We can tell you that the model is leaning Over the total, and it's also generated a point-spread pick that hits in over 70% of simulations. You can only see the pick at SportsLine.

So who wins Memphis vs. Virginia, and which side of the spread hits over 70% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model on a 176-128 roll on top-rated college basketball picks, and find out.