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The 2026 Atlantic 10 Tournament tips on Wednesday, and the first matchup is between the No. 12 seed La Salle Explorers and the No. 13 St. Bonaventure Bonnies. The Bonnies (15-16, 4-14 A-10) have the significant better season-long record, but La Salle (9-22, 5-13 A-10) edged them out by a game in the conference standings. This will be the final tournament for St. Bonaventure coach Mark Schmidt, who will retire after the season following 19 years with the program. La Salle won the regular-season matchup between these teams 78-74 on Jan. 17.

Tipoff from PPG Paints Arena is at 11:30 a.m. ET. The latest St. Bonaventure vs. La Salle odds list the Bonnies as 5.5-point favorites. The over/under is 144.5. Before making any La Salle vs. St. Bonaventure picks, check out the men's college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered conference tournament week on a sizzling 14-2 run on its top-rated over/under college basketball picks dating back to last season, and is on a 28-21 run on top-rated CBB side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.    

Now, the model has simulated St. Bonaventure vs. La Salle 10,000 times and just revealed its coveted men's college basketball picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several men's college basketball odds and men's college basketball betting lines for La Salle vs. St. Bonaventure:

St. Bonaventure vs. La Salle spread:    

St. Bonaventure -5.5

St. Bonaventure vs. La Salle over/under:    

144.5 points

St. Bonaventure vs. La Salle money line:    

St. Bonaventure -224, La Salle +184

St. Bonaventure vs. La Salle picks:    

See picks at SportsLine

St. Bonaventure vs. La Salle streaming:

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Top St. Bonaventure vs. La Salle predictions

SportsLine's model is going Under on the total (144.5 points). La Salle trended to the Under this season with 57% of its games landing on that side of the total. Two of the past three St. Bonaventure games have gone Under as well. 

The model is projecting Darryl Simmons to II to lead the Bonnies with 19 points, while Frank Mitchell adds 18.6. Rob Dockery, meanwhile, leads La Salle with 15.7 points in the simulations. The teams are projected to combine for 143 points as the Under hits 59% of the time.

How to make La Salle vs. St. Bonaventure picks

The model also says one side of the spread hits in well over 60% of simulations. You can only see that pick at SportsLine.

So who wins St. Bonaventure vs. La Salle, and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.