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A rubber match of in-state foes unfolds Friday in the quarterfinals of the 2026 SEC Tournament as the No. 4 seed Vanderbilt Commodores take on the No. 5 seed Tennessee Volunteers. These teams split the regular season series 1-1, with each winning on the road. Tennessee defeated Auburn in the second round on Thursday, while this will be Vanderbilt's first game of the SEC Tournament 2026 after earning a double-bye. 

Tipoff from Bridgestone Arena in Nashville, Tenn., is set for 3:30 p.m. ET. The latest Tennessee vs. Vanderbilt odds list the Volunteers as 1.5-point favorites, while the over/under is 146.5. Before making any Vanderbilt vs. Tennessee picks, check out the men's college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered conference tournament week on a sizzling 14-2 run on its top-rated over/under college basketball picks dating back to last season, and is on a 28-21 run on top-rated CBB side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.    

Now, the model has simulated Tennessee vs. Vanderbilt 10,000 times and just revealed its vmen's college basketball picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several men's college basketball odds and men's college basketball betting lines for Vanderbilt vs. Tennessee:

Tennessee vs. Vanderbilt spread:    

Vanderbilt -1.5

Tennessee vs. Vanderbilt over/under:    

146.5 points

Tennessee vs. Vanderbilt money line:    

Tennessee -121, Vanderbilt +101

Tennessee vs. Vanderbilt picks:    

See picks at SportsLine

Tennessee vs. Vanderbilt streaming:

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Top Vanderbilt vs. Tennessee predictions

After 10,000 simulations of Tennessee vs. Vanderbilt, SportsLine's model is going Over on the total (146.5 points). These teams met last Saturday in the regular season finale and combined for 168 points, easily clearing the total in that matchup. Tennessee also didn't have star Nate Ament due to a leg injury in that game, so the Vols should have more offensive firepower in this one. 

The model projects that Ament and Ja'Kobi Gillespie will combine for almost 36 points for Tennessee. Vanderbilt, meanwhile, gets more than 16 points from both Tyler Tanner and Duke Miles. The teams combine for 156 points as the Over hits 73% of the time.

How to make Tennessee vs. Vanderbilt picks

The model also says one side of the spread is the better value. You can only see that pick at SportsLine.

So who wins Vanderbilt vs. Tennessee, and which side of the spread is the better value? Visit SportsLine now to see which side of the spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.