NCAA Football: Texas A&M at Alabama
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Saturday's portion of the Championship Week college football schedule is full of important games, but the headliner will take place in Atlanta when No. 1 Georgia faces No. 3 Alabama in the SEC title game (4 p.m. ET, CBS). The Bulldogs rolled through the regular season with a 12-0 record, winning the final 11 games by double digits. Alabama suffered a disappointing loss to Texas A&M in the middle of the season, which means the stakes are extremely high Nick Saban's team. The Crimson Tide are 6.5-point underdogs in the latest Championship Week college football odds at Caesars Sportsbook.

Alabama has not been an underdog since 2015 when it blew out Georgia in a 38-10 final on the road. Can the Crimson Tide pick up another win over the Bulldogs? And which other college football lines have the most value on this loaded Championship Week Saturday? Before making any college football picks for Championship Week, be sure to see the latest college football predictions and betting advice from SportsLine's proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Championship Week 2021 on a 42-28 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Championship Week college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top college football predictions for Championship Week

One of the top college football picks the model is recommending for Championship Week: No. 4 Cincinnati (-10.5) covers against No. 21 Houston in the AAC Championship Game at 4 p.m. ET on Saturday. The Bearcats could be one win away from securing a spot in the College Football Playoff. They need to win this game with margin to feel comfortable about their chances, so bettors should feel equally as comfortable laying the lumber on Saturday afternoon. Cincinnati has won 26 home games in a row and is playing in its third-straight AAC title game.

Houston lost to Cincinnati by 18 points last season and fell to Texas Tech by 17 points earlier this season. SportsLine's model expects the Bearcats to control the tempo with its rushing attack, as running back Jerome Ford is projected to rush for nearly 80 yards and one touchdown. The Bearcats are covering the spread in 60 percent of simulations, while the over (53) is hitting more than 50 percent of the time. 

Another one of the college football predictions from the model: No. 5 Oklahoma State (-5.5), fresh off a massive Bedlam win over rival Oklahoma, continues its roll and knocks off the No. 9 Baylor Bears in the Big 12 Championship Game at noon ET on Saturday. The Cowboys have been one of the best teams to back in college football this season, covering the spread in nine of their 12 games. 

They have won the last two meetings between these teams, including a 24-14 win over Baylor earlier this year. Senior running back Jaylen Warren rushed for 125 yards and two touchdowns in that game, which allowed the Cowboys to control the tempo. Baylor quarterback Gerry Bohanon completed just 13 of 27 passes against Oklahoma State's defense in the loss and he's questionable with a hamstring injury. The Cowboys are covering the spread in almost 60 percent of simulations, while the under (46.5) is cashing nearly 60 percent of the time as well. 

How to make Championship Week college football picks 

The model has also made the call on who wins and covers in every other game during the Championship Week college football schedule, and it's projecting multiple underdogs to win outright. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence? And which underdogs do you need to jump on now? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,700 in profit over the past five-plus seasons, and find out.

Championship Week college football odds (via Caesars)

Here are the college football lines for Championship Week:

Saturday, Dec. 4

MAC: Kent State vs. Northern Illinois (+3, 72.5)

Featured Game | Northern Illinois Huskies vs. Kent State Golden Flashes

Big 12: Baylor vs. Oklahoma State (-5.5, 46.5)

Featured Game | Oklahoma State Cowboys vs. Baylor Bears

Mountain West: Utah State vs. San Diego State (-6, 50.5)

Featured Game | San Diego State Aztecs vs. Utah State Aggies

Sun Belt: Appalachian State vs. Louisiana (+3, 52.5)

Featured Game | Louisiana Ragin' Cajuns vs. Appalachian State Mountaineers

SEC: Georgia vs. Alabama (+6.5, 50)

Featured Game | Alabama Crimson Tide vs. Georgia Bulldogs

AAC: Houston vs. Cincinnati (-10.5, 54)

Featured Game | Cincinnati Bearcats vs. Houston Cougars

ACC: Pittsburgh vs. Wake Forest (+3, 72.5)

Featured Game | Wake Forest Demon Deacons vs. Pittsburgh Panthers

Big Ten: Michigan vs. Iowa (+10.5, 43.5)

Featured Game | Iowa Hawkeyes vs. Michigan Wolverines

USC vs. California (-2.5, 57.5)

Featured Game | California Golden Bears vs. USC Trojans