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The Colorado Buffaloes (2-1) and Baylor Bears (2-1) will meet in a Big 12 conference opener on Saturday night in Boulder. Colorado bounced back from a 28-10 loss to Nebraska with a 28-9 road win at Colorado State last week to claim the Rocky Mountain Showdown. Baylor lost at then-No. 11 Utah two weeks ago before picking up a 31-3 win over Air Force. This is the first meeting between these teams since 2010, when Baylor notched a 31-25 road victory. 

Kickoff is set for 8 p.m. ET on Saturday at Folsom Field. Colorado is favored by 1.5 points in the latest Colorado vs. Baylor odds, while the over/under is 52.5 points, per SportsLine consensus. Before entering any Baylor vs. Colorado vs. picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 5-2 start on over/under picks this season. Anyone who has followed it has seen strong returns.

The model has set its sights on Baylor vs. Colorado. You can head to SportsLine to see its picks. Here are several college football betting lines for the game:

  • Colorado vs. Baylor spread: Colorado -1.5
  • Colorado vs. Baylor over/under: 52.5 points
  • Colorado vs. Baylor money line: Colorado -125, Baylor +104
  • Colorado vs. Baylor picks: See picks here

Why Colorado can cover

Colorado struggled to establish its rushing attack in its first two games of the season, but it ran for a season-high 116 yards in a 28-9 win over rival Colorado State last week. This makes the Buffaloes a potent offense, as quarterback Shedeur Sanders has completed 70.2% of his passes for 999 yards, nine touchdowns and two interceptions. 

Two-way star Travis Hunter has caught 30 passes for 342 yards and five touchdowns, while wide receiver Jimmy Horn Jr. has 246 receiving yards and a score. Baylor is going on the road for just the second time this season after losing to Utah by double digits two weeks ago. The Bears are winless in their last 10 games against Big 12 opponents. See which team to pick here. 

Why Baylor can cover

Baylor bounced back nicely from its loss to Utah, cruising to a 31-3 win over Air Force as a 17-point favorite. Sawyer Robertson stepped in as the starting quarterback in place of an injured Dequan Finn, completing 18 of 24 passes for 248 yards with a rushing touchdown. Head coach Dave Aranda has listed both quarterbacks as options on the depth chart for this game. 

Aranda took over the defensive play calling duties this season, and the Bears have allowed the fewest passing yards per game (75.7) in the country. Colorado attempted to fix its offensive line issues in the offseason, but it has already allowed seven sacks in three games. The Buffaloes have won two of their last nine games dating back to last season, while Baylor has covered the spread in four of its last five games. See which team to pick here. 

How to make Colorado vs. Baylor picks

The model has simulated Baylor vs. Colorado 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50% of simulations. You can only see the pick at SportsLine.

So who wins Colorado vs. Baylor, and which side of the spread is hitting over 50% of the time? Visit SportsLine now to see which side of the Baylor vs. Colorado spread to jump on, all from the advanced computer model that's up over $2,000 on its top-rated college football spread picks since its inception, and find out.