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Deion Sanders and the Colorado Buffaloes (2-1) look to take another step towards bowl eligibility when they travel to the Sunshine State to take on the UCF Knights (3-0) in Orlando on Saturday. The Buffs won their last game against Baylor 38-31 behind an improbable comeback that featured a Hail Mary touchdown pass from Shedeur Sanders and a forced fumble by Heisman Trophy candidate Travis Hunter in overtime. The Knights have had two weeks to prepare for this matchup, and defeated TCU 35-34 in their last outing. UCF leads the nation in rushing offense, averaging 375.7 yards per game on the ground. This will be the first meeting between the programs.

Kickoff in Orlando is scheduled for 3:30 p.m. ET. The Knights are 14-point favorites in the latest Colorado vs. UCF odds via SportsLine consensus, and the over/under is 62 points. Before making any UCF vs. Colorado picks, you need to see the Week 4 college football predictions and betting advice from SportsLine's Jimmie Kaylor

Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor destroyed the books in college football in 2023, netting a whopping 57.9 units while posting a 107-45-2 record. Anyone who followed his picks finished the season way up.

Now, Kaylor has dialed in on Colorado vs. UCF on Saturday and just revealed his picks and predictions. You can head to SportsLine now to see his picks. Here are the college football odds and college football betting lines on the spreadmoney line, and over/under for UCF vs. Colorado:

  • Colorado vs. UCF spread: UCF -14
  • Colorado vs. UCF over/under: 62 points 
  • Colorado vs. UCF money line: UCF -568, Colorado +408
  • Colorado vs. UCF picks: See picks at SportsLine

Why Colorado can cover

The Buffs have one of the most explosive offenses in college football. Led by senior quarterback Shedeur Sanders, CU ranks fifth in the country averaging 335.0 passing yards per game this season. Sanders has completed 67.9% of his passes for 1,340 yards, 11 touchdowns, and two interceptions. He's also scored one rushing touchdown.

Colorado also has the ultimate X-factor in two-way star Travis Hunter. The former five-star recruit has 37 catches for 472 yards and five touchdowns (all team highs) as a wide receiver, and he has 14 tackles, one forced fumble, and one interception as a defensive back. The Knights will have to know where Hunter is at on the field for the entirety of the Saturday's game. See which team to pick here.

Why UCF can cover

The Knights have had two weeks to prepare for this matchup, and have been dominant at home this season. In two games at FBC Mortgage Stadium in 2024, UCF has outscored its opponents 102-17. Knights head coach Gus Malzahn is widely considered to be one of the top offensive minds in college football. 

The Knights have been the best rushing team in the country this season. UCF is averaging 375.7 rushing yards per game in 2024, and the Buffs haven't been particularly strong defending the run this season, allowing 150.8 rushing yards per game. Senior running back RJ Harvey leads the way for the Knights with 448 rushing yards and eight rushing touchdowns on 49 carries. See which team to pick here.

How to make UCF vs. Colorado picks

Kaylor has analyzed Colorado vs. UCF from every angle and he's leaning Under on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.

So who wins Colorado vs. UCF on Saturday in Orlando, and what critical X-factor makes one side of the spread a must back? Visit SportsLine now to see which side of the spread to jump on, all from the expert who profited $5,790 for $100 college football bettors in 2023, and find out.