The No. 17 Kansas State Wildcats will visit the Houston Cougars in a Big 12 battle on Saturday afternoon. K-State (7-1, 4-1) has won four straight games and is 3-1 on the road this season. Houston (3-5, 2-3) has won two of its last three and has split its four home games in 2024. This is just the second all-time meeting between the programs, and KSU rolled to a 41-0 shutout victory when they met last season. 

Kickoff is at 3:30 p.m. ET at TDECU Stadium in Houston. KSU is favored by 13 points in the latest Houston vs. Kansas State odds, per SportsLine consensus, after opening as 10.5-point favorites. The over/under is 45.5 points. Before entering any Kansas State vs. Houston picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 16-7 on all top-rated picks over the past five weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.

The model has set its sights on Kansas State vs. Houston. You can head to SportsLine to see its picks. Here are several college football betting lines for K-State vs. Houston:

  • Houston vs. Kansas State spread: Kansas State -13
  • Houston vs. Kansas State over/under: 45.5 points
  • Houston vs. Kansas State money line: Kansas State -543, Houston +393
  • UH: The Under is 7-1 for the Cougars this season
  • KSU: The Wildcats are 1-3 against the spread on the road in 2024
  • Houston vs. Kansas State picks: See picks at SportsLine
  • Houston vs. Kansas State streaming: FuboTV (Try for free)

Why Kansas State can cover

K-State is coming off a 29-27 victory over rival Kansas in which quarterback Avery Johnson had 253 yards and two touchdowns thru the air, with 67 yards and a score on the ground. Kansas State also got a significant boost from running back DJ Giddens, who ran away from the competition to the tune of 102 yards, while wideout Jayce Brown topped the Wildcats with 98 receiving yards. Colorado transfer Dylan Edwards also has a productive game with 60 rushing yards, 20 receiving yards and 28 return yards.

KSU is averaging 223.3 rushing yards per game, which ranks third amongst Power Four teams. Johnson is a big part of that, and he's elevated his game during the Wildcats' four-game winning streak. He's accounted for 14 total touchdowns versus just two interceptions over this stretch, and he also has help on the defensive side of the ball. Defensive end Brendan Mott leads the Big 12 with 7.0 sacks, and he'll be licking his chops at facing a Houston team which allowed seven sacks in a loss to Kansas two weeks ago. See which team to pick here.

Why Houston can cover

Meanwhile, there's no place like home for Houston, who bounced back after a tough loss on the road last Saturday. It came out on top in a nail-biter against Utah on Saturday, sneaking past 17-14. The Coogs racked up 230 rushing yards, marking the third time over the last six games they've topped 200 on the ground. Defensive back A.J. Haulcy had his third interception over the last three games as the New Mexico transfer ranks fifth in FBS with four picks on the year.

This is the fifth time that Houston is a double-digit home favorite over the last 20 years, and it has covered in three of the previous four. Meanwhile, KSU not only failed to cover in its last game as a double-digit road favorite -- which came in 2023 -- but the Wildcats lost outright. Additionally, K-State is only 1-6 against the spread as a road favorite since the start of last season, with that 14.3% cover rate being the second-worst in the nation (min. five games). See which team to pick here.

How to make Houston vs. K-State picks

The model has simulated K-State vs. Houston 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in nearly 60% of simulations. You can only see the pick at SportsLine.

So who wins Houston vs. KSU, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the KSU vs. Houston spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out.