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The 16th-ranked LSU Tigers battle the South Carolina Gamecocks in SEC action on Saturday in Columbia, S.C. It will be the conference opener for LSU. The Tigers (1-1), who are looking for their third consecutive 10-win season, are coming off a 44-21 win over Nicholls last Saturday. The Gamecocks (2-0), who finished 5-7 a year ago, have not won more than 10 games in a season since going 11-2 in 2013.

Kickoff from Williams-Brice Stadium is set for noon ET. LSU is averaging 399.5 yards per game, while South Carolina averages 270. The Tigers are favored by 6.5 points in the latest LSU vs. South Carolina odds via SportsLine consensus, while the over/under for total points scored is 49.5. Before making any LSU vs. South Carolina picks, check out the college football predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 4-0 start on over/under picks this season. Anyone who has followed it has seen strong returns.

The model has set its sights on LSU vs. South Carolina. You can head to SportsLine to see its picks. Here are several college football betting lines for the spreadmoney line and over/under for the game: 

  • LSU vs. South Carolina spread: LSU -6.5
  • LSU vs. South Carolina over/under: 48 points
  • LSU vs. South Carolina money line: LSU -240, South Carolina +193
  • LSU: The Tigers have hit the game total over in 11 of their last 13 games (+8.80 units)
  • SC: The Gamecocks have hit the first-quarter money line in nine of their last 12 games (+11.40 units)
  • LSU vs. South Carolina picks: See picks at SportsLine

Why you should back LSU

Sophomore wide receiver Aaron Anderson is making his mark this season. He is coming off a five-catch, 63-yard performance in a 44-21 win over Nicholls last Saturday. In the 27-20 opening-game loss to Southern Cal, Anderson had five receptions for 64 yards and one score, including a long of 41 yards. For his career, Anderson has 22 receptions for 186 yards (8.5 average) and one touchdown.

Senior defensive end Sai'vion Jones has been a beast on defense and leads the team with a pair of sacks for eight yards. They both came in the opener against USC. In two games, he has registered seven tackles, including four solo, with one forced fumble and one pass breakup. In four seasons with the Tigers, he has recorded 65 tackles, including 24 solo, with nine sacks, two forced fumbles and four pass breakups. See which team to pick here.

Why you should back South Carolina

Wide receiver Mazeo Bennett Jr. has started his collegiate career in a big way. In the opening 23-19 win over Old Dominion, the freshman caught two passes for 18 yards. He followed that up in a 31-6 win over Kentucky by catching three passes for 63 yards and a score. He is ranked 19th in the SEC in receiving yards per reception at 16.2.

The Gamecocks defense has been stellar. They have a pair of edge rushers who have combined to register six sacks for 45 yards. Freshman Dylan Stewart has 2.5 sacks for 26 yards and two forced fumbles. Senior Kyle Kennard has 3.5 sacks for 19 yards and two forced fumbles. Through two games, South Carolina has 10 sacks and six forced fumbles. See which team to pick here.

How to make LSU vs. South Carolina picks

SportsLine's model is leaning Over on the total, projecting 48 combined points. It also says one side of the spread is the better value. You can only get the pick at SportsLine.

So who wins LSU vs. South Carolina, and which side of the spread is the better value? Visit SportsLine now to see which side of the LSU vs. South Carolina spread to jump on, all from the advanced model that is up over $2,000 on its FBS college football picks since its inception, and find out.