Michigan quarterback Jack Tuttle is retiring from football due to a string of concussions and other health issues.

In an Instagram post announcing his retirement, Tuttle said he recently suffered the fifth concussion of his college career. Tuttle, after dealing with an elbow injury over the past year, played against Washington and Illinois earlier this month but was ruled out of Michigan's game against Michigan State last weekend.

"The past year has been challenging, marked by a UCL repair in my throwing arm that I didn't fully recover from, which has caused ongoing issues," Tuttle wrote. "And unfortunately, the recent experience of enduring my fifth concussion has brought forth the painful truth: that I need to start prioritizing my health. Throughout my college career, l've battled numerous injuries, culminating in this difficult choice to step away from playing the game that I love."

Tuttle made his first appearance of the season in Week 6 against Washington and started two weeks later against Illinois. Tuttle completed 20 of 32 attempts for 208 yards and an interception in a 21-7 loss to Illinois. The Wolverines turned back to Davis Warren -- their Week 1 starter -- in the 24-17 win over Michigan State last weekend.

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Tuttle signed with Utah out of high school and then spent four seasons at Indiana before arriving at Michigan in 2023. He finished his career with 1,337 passing yards and seven touchdowns. Tuttle wrote in his retirement post that he plans on pursuing a role in coaching.

With Tuttle retiring, Michigan will likely continue to start Warren at quarterback. The Wolverines have used three different starting quarterbacks this season -- Warren, Tuttle and Alex Orji, who served as last season's backup to first-round pick J.J. McCarthy during Michigan's run to the national title.

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Now 5-3 on the year, Michigan is set to host No. 1 Oregon on Saturday in Ann Arbor (3:30 ET on CBS).