No. 17 Notre Dame (2-1) will try to build on its best performance of the season when it hosts Miami (OH) (0-2) on Saturday afternoon. The Fighting Irish bounced back from their shocking loss to Northern Illinois with a 66-7 win at Purdue last week. They were only 7.5-point favorites, but they raced out to a 42-0 lead at halftime. Miami is getting set for its third consecutive game as an underdog following losses to Northwestern and Cincinnati. 

Kickoff is set for 3:30 p.m. ET on Saturday at Notre Dame Stadium. Notre Dame is favored by 27.5 points in the latest Notre Dame vs. Miami (OH) odds, while the over/under is 43.5 points, per SportsLine consensus. Before entering any Miami of Ohio vs. Notre Dame picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 5-2 start on over/under picks this season. Anyone who has followed it has seen strong returns.

The model has set its sights on Miami of Ohio-Notre Dame. You can head to SportsLine to see its picks. Here are several college football betting lines for the game:

  • Notre Dame vs. Miami of Ohio spread: Notre Dame -27.5
  • Notre Dame vs. Miami of Ohio over/under: 43.5 points
  • Notre Dame vs. Miami of Ohio money line: Notre Dame -6250, Miami (OH) +1804
  • Notre Dame vs. Miami of Ohio picks: See picks here

Why Notre Dame can cover

Notre Dame had its College Football Playoff hopes damaged by a 16-14 loss to Northern Illinois two weeks ago, but it bounced back with an outstanding performance against Purdue. The Fighting Irish handed Purdue its most lopsided loss in school history, racking up 362 rushing yards. They had 278 of those yards in the first two quarters before their starters rested in the second half. 

It was also Notre Dame's highest point total since a 66-14 win against New Mexico in 2019, as running back Jeremiyah Love had 11 carries for a career-best 109 yards. Quarterback Riley Leonard added 100 rushing yards and three touchdowns while passing for 112 yards. The Fighting Irish have now covered the spread in five of their last six games dating back to the end of last season. See which team to pick here.

Why Miami OH can cover

As impressive as Notre Dame was last week, its abysmal performance against Northern Illinois two weeks ago cannot be forgotten. The Fighting Irish were 28-point favorites in that game, so it was a similar situation to this game. Miami entered the season with College Football Playoff aspirations as the top Group of Five school, but it has not been able to live up to expectations thus far. 

The RedHawks lost to Northwestern by a touchdown before falling to Cincinnati by 11 points last week. They are led by an experienced quarterback in senior Brett Gabbert, who has thrown for 566 yards and two touchdowns. Miami has covered the spread in 11 of its last 15 games, including four of its last five in September. See which team to pick here. 

How to make Notre Dame vs. Miami of Ohio picks

The model has simulated Miami OH vs. Notre Dame 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You can only see the pick at SportsLine.

So who wins Notre Dame vs. Miami OH, and which side of the spread is hitting well over 60% of the time? Visit SportsLine now to see which side of the Miami OH vs. Notre Dame spread to jump on, all from the advanced computer model that's up over $2,000 on its top-rated college football spread picks since its inception, and find out.