The first year of the expanded College Football Playoff has arrived, with four first-round games set for this weekend. No. 7 seed Notre Dame host No. 10 seed Indiana in the lone game on Friday night at 8 p.m. ET, with the Fighting Irish favored by 6.5 points in the latest college football odds from SportsLine consensus. Notre Dame closed the regular season on a 10-game winning streak, but this is its first game against a top-15 team this season. Which team should you pick with your 2024-25 college football score predictions?

The action continues on Saturday with No. 6 Penn State (-8.5) vs. No. 11 SMU, No. 5 Texas (-12.5) vs. No. 12 Clemson and No. 8 Ohio State (-7.5) vs. No. 9 Tennessee. There are also plenty of college football bowl games scattered throughout this week's college football schedule as well. Before making any college football bowl picks or College Football Playoff score predictions, you need to see the college football against the spread, over/under and money-line predictions powered by the self-learning SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

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In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has hit a whopping 2,131 4.5- and 5-star NFL picks since the start of last season. Anyone who has followed it is way up at their best sports betting app and favorite betting sites

For CFP and bowl season college football betting, the AI PickBot has evaluated the college football odds and provided college football betting picks for every bowl game. You can only see the AI predictions for the college football bowl schedule here.

Top college football AI picks for bowl season

After analyzing every college football bowl game, the AI PickBot says the No. 12 seed Clemson Tigers (+12.5, 51) cover comfortably on Saturday against the No. 5 seed Texas Longhorns in the first round of the College Football Playoff at 4 p.m. ET. Clemson lost three games during the regular season, but it was able to secure a spot in the CFP with a win over SMU in the ACC Championship. The Tigers are led by star quarterback Cade Klubnik, who has completed 63.7% of his passes for 3,303 yards and 33 touchdowns. 

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Klubnik has also done an excellent job taking care of the ball, throwing just five interceptions this season. He has added 458 rushing yards and seven touchdowns on the ground, creating a tricky matchup for Texas. The AI PickBot has identified value on Clemson to stay within the spread, projecting the Longhorns to win by an average final score of 29-25 to earn a B rating. See its other college football bowl predictions and football picks at SportsLine.

How to make college football bowl picks

In addition, the AI PickBot has generated six more highly-rated spread picks for the first week of college football bowl season. You need to see the AI PickBot's college football picks before making any college football bowl bets of your own. You can only see them at SportsLine.

Who wins and covers each college football bowl game? Visit SportsLine now to see the top college football picks against the spread, over/under, and on money line, all from the SportsLine AI PickBot that has nailed 2,131 top-rated NFL picks since the start of last season.

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