diego-pavia-vanderbilt-commodores
Imagn Images

Tennessee and Vanderbilt meet for the 119th time on Saturday, and it is one of the most important matchups in the history of the series. Both sides are ranked for the first time ever in this game, and a win for No. 14 Vanderbilt could send the Commodores to the College Football Playoff. The three-loss Vols, who are ranked No. 19, fell out of the playoff picture after falling to Oklahoma earlier this month. The Vols, however, bounced back with their first win at Florida since 2003 last week and can play playoff spoiler against their in-state foe. Tennessee running back Peyton Lewis is listed as questionable.

Kickoff is at 3:30 p.m. ET from Neyland Stadium in Knoxville, Tenn. The Vols are 2.5-point favorites in the latest Tennessee vs. Vanderbilt odds, while the over/under is 66.5. Before making any Vanderbilt vs. Tennessee picks, check out the college football predictions from the SportsLine Projection Model

New users can target the DraftKings promo code, which offers $200 in bonus bets if your bet wins + 3 months of NBA League Pass:

The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.

Now, the model has set its sights on Tennessee vs. Vanderbilt. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for Vanderbilt vs. Tennessee:

Tennessee vs. Vanderbilt spread

Tennessee -2.5

Tennessee vs. Vanderbilt over/under

66.5 points

Tennessee vs. Vanderbilt money line 

Tennessee -141, Vanderbilt +118

Tennessee vs. Vanderbilt picks

See picks at SportsLine

Tennessee vs. Vanderbilt streaming 

Fubo (Try for free)  

How to make Tennessee vs. Vanderbilt picks

SportsLine's model has simulated Vanderbilt vs. Tennessee 10,000 times and is going Under 66.5 total points. Tennessee's defense has improved in recent weeks, giving up an average of just 10 points per game in its past two outings, with both of those games going Under the total.

Vanderbilt has trended to the Over in its games this year, but has split Over and Under in four road games. These teams combined for 59 points last year as Pavia had just 104 passing yards in that game. SportsLine's model projects 62 points this year as the total goes Under nearly 60% of the time. 

The model also says one side of the spread hits nearly 60% of the time. You can only get the pick at SportsLine.   

So who wins Vanderbilt vs. Tennessee, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season, and find out.