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The Charlotte 49ers look to snap a two-game losing streak when they host the Tulane Green Wave on Thursday night. Charlotte is 3-5, including 2-2 in the American Athletic Conference. The 49ers' season has been highlighted by a 55-24 victory over East Carolina as 9-point underdogs on Oct 5. Meanwhile, Tulane is 29-7 since the start of the 2022 season, including 19-1 in AAC play. The Green Wave are 6-2 this season and enter Thursday's bout having won five straight.

Kickoff is set for 7:30 p.m. ET from Jerry Richardson Stadium in Charlotte, N.C. The Green Wave are 15-point favorites according to the latest Charlotte vs. Tulane odds via the SportsLine consensus, while the over/under for total points scored is 54.5. Before making any Tulane vs. Charlotte picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 16-7 on all top-rated picks over the past five weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.

Now, the model has dialed in on Charlotte vs. Tulane and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college football betting lines and trends for Tulane vs. Charlotte:

  • Charlotte vs. Tulane spread: Green Wave -15
  • Charlotte vs. Tulane over/under: 54.5 points 
  • Charlotte vs. Tulane money line: Green Wave -694, Owls +486
  • TUL: Tulane is 4-1 ATS over its last five games 
  • CHA: Charlotte is 3-1 ATS over its last four games
  • Charlotte vs. Tulane picks: See picks here
  • Charlotte vs. Tulane streaming: FuboTV (Try for free)

Why Tulane can cover

The Green Wave have been dominant in AAC play this season, going 4-0 with victories by an average of 27 points. Tulane is winning behind the dynamic rushing ability of sophomore running back Makhi Hughes, who has rushed for more than 115 yards in four of his last five games. Hughes is averaging 117.4 rushing yards per contest, including 167.5 yards over his last two games. The speedy 5-foot-11 back rushed for 195 yards on 30 carries for 6.5 yards per rush and a touchdown against North Texas last week.

Tulane rushes on 64.5% of plays, the fourth-most in college football, and ranks 10th in rushing yards (213.3 per game). Those are largely scripted running back carries as redshirt freshman quarterback Darian Mensah isn't much of a runner. He's averaging three rushes per game over his last four contests. Charlotte ranks outside the top 100 in nearly every defensive rushing statistic, including 118th in rushing yards allowed per game (203.6) in what appears to be a challenging matchup for the 49ers. See who to back at SportsLine.

Why Charlotte can cover

Charlotte has struggled to move the ball consistently in games this season, but once the 49ers get inside the 20-yard line, they are one of the more efficient teams in the nation in exiting with points. Charlotte has scored on 88.9% of red zone opportunities, which is 40th in college football. With a spread of more than two scores against Tulane, if Charlotte can capitalize on a few red zone possessions, that can be enough to cover the margin on Thursday.

Although Charlotte has only one winning season in its previous nine years, the 49ers have already matched their win total from the last two seasons. That shows improvement in the program in Biff Poggi's second year as head coach and outside of a 51-17 loss to No. 25 Navy, Charlotte is 2-1 since September 28. Its one loss came in a five-point game to Memphis where the 49ers led with less than two minutes remaining. Charlotte is averaging 30.3 points over its last four games, so the 49ers can keep up with Tulane on Thursday night. See who to back at SportsLine.

How to make Charlotte vs. Tulane picks

SportsLine's model is leaning Over on the total, projecting 63 combined points. It also says one side of the spread hits in 70% of simulations. You can see the model's pick at SportsLine.

So who wins Tulane vs. Charlotte, and which side of the spread hits 70% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out.