Weisser was 11-of-16 passing for 143 yards, completing at least one pass to 10 different receivers. He capped a 12-play, 79-yard drive to open the game with a 1-yard touchdown run and scored on a 4-yard run early in the second quarter to make it 14-7 and Weber State (2-3, 1-1 Big Sky) led the rest of the way.
Weisser threw an 18-yard touchdown pass to Dave Jones midway through the period and Winston Reid's strip-sack of Cal Poly's Jackson Pavitt led to a 2-yard fumble return for a score by B.J. Taulele that made it 28-7 with 42 seconds left in the half.
Cal Poly (1-4, 0-2), finished with just 115 total yards, has lost four straight since a season-opening win over San Diego.
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