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Two of the top teams in Conference USA clash on Wednesday night when the Western Kentucky Hilltoppers face the Sam Houston Bearkats. Both teams are coming off big wins over UTEP in their last game. Western Kentucky rolled to a 44-17 triumph on Thursday, while Sam Houston registered a 41-21 win on Oct. 3, before having its bye. The Hilltoppers (4-2, 2-0 C-USA), who have won four conference games in a row dating back to last year, are allowing just 23.8 points per game. The Bearkats (5-1, 2-0 C-USA), who have a three-game conference winning streak since 2023, are also allowing 23.8 points per game.

Kickoff from Elliott T. Bowers Stadium in Huntsville, Texas, is set for 7 p.m. ET. The Bearkats are favored by 2.5 points in the latest Western Kentucky vs. Sam Houston odds, while the over/under for total points scored is 55.5. Before making any Sam Houston vs. Western Kentucky picks, check out the college football predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 12-5 on all top-rated picks over the past three weeks of this season. Anyone who has followed it has seen strong returns.

The model has set its sights on WKU vs. Sam Houston. You can head to SportsLine to see its picks. Here are several college football betting lines and trends for Sam Houston vs. WKU:

  • Western Kentucky vs. Sam Houston spread: Sam Houston -2.5
  • Western Kentucky vs. Sam Houston over/under: 55.5 points
  • Western Kentucky vs. Sam Houston money line: Sam Houston -134, WKU +112
  • WKU: Have covered in five straight 
  • SH: The Bearkats are 5-1 ATS this season 
  • Western Kentucky vs. Sam Houston picks: See picks at SportsLine
  • Western Kentucky vs. Sam Houston streaming: FuboTV (Try for free)

Why you should back Sam Houston

The Bearkats have a dual threat in junior quarterback Hunter Watson. He not only leads the team in passing, but is also the leading rusher. He has completed 78 of 132 pass attempts (59.1%) for 859 yards and seven touchdowns with five interceptions and a 123.7 rating. He also has a team-high 84 carries for a team-high 370 yards (4.4 average) and four touchdowns. He has two 200-yard passing games and two 100-yard rushing performances.

Qua'Vez Humphreys is among Sam Houston's leading receivers. The junior is in his first season with the Bearkats and has 12 receptions for a team-high 281 yards (23.4 average) and four touchdowns. In the win at UTEP, he caught two passes for 47 yards and a touchdown. He had four catches for 106 yards (26.5 average) and two touchdowns in a 31-13 win over Hawaii on Sept. 14. See which team to pick here.

Why you should back Western Kentucky

Sophomore quarterback Caden Veltkamp helps power the offense. He leads the team in passing and is fourth in rushing. For the year, he has completed 94 of 135 passes (69.6%) for 1,147 yards and 11 touchdowns with five interceptions for a rating of 160.5. He has carried 44 times for 71 yards (1.6 average) and four touchdowns. In the win over UTEP, he completed 18 of 27 passes (66.7%) for 264 yards and three touchdowns with one pick. He also carried 13 times for 29 yards and a score.

Veltkamp's favorite target has been senior wide receiver Kisean Johnson. Johnson has had two 100-plus-yard games already this season, including an eight-catch, 129-yard and two-touchdown effort in a 49-21 win at Middle Tennessee State on Sept. 14. He caught six passes for 119 yards (19.8 average) in a 31-0 win over Eastern Kentucky on Sept. 7. For the season, he has 34 receptions for 474 yards (13.9 average) and four touchdowns. See which team to pick here.

How to make Western Kentucky vs. Sam Houston picks

SportsLine's model is leaning Under on the total, projecting 55 combined points. It also says one side of the spread hits well over 50% of the time. You can only get the pick at SportsLine.

So who wins Western Kentucky vs. Sam Houston, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on its FBS college football picks since its inception, and find out.