Santiago (2-1) surrendered eight hits, four earned runs and a walk over 5.2 innings in a 4-2 loss to the Rangers on Friday.
The 28-year-old had his shortest stint of his first five starts in 2016, and the four earned runs he surrendered equaled his highest tally to date. After notching 17 whiffs over the last 13 innings prior to Friday's start, Santiago also pitched a lot more to contact, inducing only four swings and misses and striking out just one. He'll try to get back in the win column in his next start, which comes Wednesday in Milwaukee.