The Astros activated Pena (calf) from the 10-day injured list Friday, Matt Kawahara of the Houston Chronicle reports.
Houston DFA'd Braden Shewmake in a corresponding move. Pena hasn't played since June 28 due to a mild left calf strain, but he's ready to return to the lineup after missing just 11 days of action. The shortstop is slashing .295/.356/.443 with six homers, 21 RBI, 34 runs scored, eight stolen bases and a 15:35 BB:K across 202 plate appearances this season.