Pena (hamstring) will start at shortstop and bat leadoff in Monday's game against the Marlins, Chandler Rome of The Athletic reports.
Pena will make his return to the starting nine after the Astros opted to keep him on the bench for Sunday's 5-2 loss to the Orioles while he managed a right hamstring cramp. Since coming off the injured list July 10 after he had been shelved with a calf strain, Pena has gone 5-for-17 (.294 average) with two walks, three runs and one RBI in five games.