Pena will sit Wednesday against the Athletics.
Pena will sit after he went 3-for-8 with a solo home run, a double and three runs scored over the first two games of the series. The 24-year-old currently owns a eight-game hit streak, batting .303 with three homers, four RBI and six runs over that stretch. Mauricio Dubon will take over at shortstop and bat seventh in the series finale.