Altuve is dealing with a right knee sprain, Brian McTaggart of MLB.com reports.
Altuve underwent an MRI on Friday, and manager Dusty Baker said that his injury was revealed to be a knee sprain. He's not in the lineup Friday and is unlikely to play during the Astros' weekend series against the Yankees. Aledmys Diaz should fill in at second base while Altuve is sidelined.