Brantley served as the designated hitter and went 0-for-4 in Wednesday's 7-0 loss to the Rays.
Brantley was reinstated off the injured list Wednesday after missing two-plus weeks due to a knee injury. The progress he made while rehabbing slowed, but Brantley is available to DH for now. His return should give a boost to Houston, which has lost five of its last six while scoring just 12 runs in the process.