The Astros activated Blanco (elbow) from the 60-day injured list Monday, Brian McTaggart of MLB.com reports.
Blanco will start Monday's game versus the Marlins, marking his first time on a big-league mound since he underwent Tommy John surgery with an internal brace last June. The 32-year-old right-hander went 4.1 innings and threw 68 pitches in his final rehab outing, so he will be relatively limited from a workload perspective as he takes on Miami.