Axford was placed on the 10-day disabled list Wednesday with a strained shoulder, MLB.com's Jane Lee reports.
Axford hadn't pitched in either of the Athletics' first two games, so it seems likely that he may have been nursing the injury coming out of spring training. Though the Athletics' closing situation remains quite unsettled, it's unlikely that Axford will get a chance to throw his hat in the ring for those duties once he's healthy again after submitting an unremarkable 3.97 ERA and 1.45 WHIP over 65.2 innings last season.