Ryu will be starting Opening Day against the Rays on Friday, Keegan Matheson of MLB.com reports.
The 33-year-old inked a four-year, $80 million deal with the Blue Jays in December, so it's no surprise he'll be opening Toronto's season on the mound. Ryu threw 80 pitches over five innings during Saturday's intrasquad game, so he shouldn't face any significant workload restrictions early in the campaign.