Guillorme will start at second base and bat eighth Tuesday against the Astros.
The 29-year-old saw his first plate appearances of the season Monday, going 1-for-3 with two strikeouts, and he's now poised for more playing time after Ozzie Albies (toe) was placed on the 10-day injured list Tuesday. Guillorme could fill the large side of a platoon at second base along with David Fletcher, who replaced Albies on the major-league roster.