The Cardinals have set their rotation for the big weekend series against the Pirates. Carlos Martinez, who was skipped on Tuesday due to a back injury, will open the series on Friday.

Jaime Garcia and John Lackey will follow on Saturday and Sunday respectively, according to MLB.com.

The Cardinals enter play on Wednesday six games ahead of the Pirates in the National League Central, with six more head-to-head matchups left on the schedule for 2015.