The Cubs optioned Ramirez to Double-A Knoxville on Sunday.
The 21-year-old infielder was added to the Cubs' 40-man roster over the winter but will need more seasoning in the upper levels of the minors before receiving his first taste of the big leagues. Ramirez will return to Knoxville for a second straight season after slashing .280/.346/.386 with eight home runs and 28 stolen bases across 563 plate appearances in the Southern League in 2025.