Astros pitcher Dallas Keuchel was not at his best on Saturday, suffering his first loss of the season in a 5-1 defeat to the Angels.

Making his first start of the season, Keuchel (0-1) allowed a run-scoring double to Howie Kendrick in the second, a run-scoring single to David Freese and a two-run home run to Josh Hamilton in the fifth inning. He allowed four runs on eight hits and two walks while striking out five over five innings pitched.

Keuchel will look to get back on track Thursday at Toronto.