The Giants placed Murphy on the 10-day injured list with a left knee sprain Sunday, Shayna Rubin of the San Francisco Chronicle reports.
Murphy suffered the injury during Saturday's contest and is now on the injured list after an MRI revealed a sprain. Patrick Bailey (concussion) is also unavailable, leaving Blake Sabol and Jakson Reetz, who had his contract selected from Triple-A Sacramento on Sunday, to handle catching duties.