Genao started at second base and went 1-for-5 with a double, an RBI and a run scored in Wednesday's 6-4 win over Detroit.
Genao replaced the primary second baseman, Travis Bazzana, for the second time in the last three games in which the Guardians faced a left-handed starter. Bazzana has a .192./.306/.240 slash line over 121 plate appearances against lefties. The switch-hitting Genao logged an .881 OPS against left-handers while with Triple-A Columbus prior to his call-up to Cleveland.