Cantillo is no longer starting Wednesday's game against the Reds and will instead pitch in Friday's series opener versus the Astros, Zack Meisel of The Athletic reports.
The Guardians have locked up a first-round bye for the postseason, so they're switching up their pitching plans in the final week of the regular season. Andrew Walters will now serve as the Guardians' opening pitcher Wednesday in what's expected to be a bullpen game. While Cantillo will pitch Friday, it's uncertain whether he'll be deployed as a traditional starter or a bulk reliever.