The Guardians acquired Lowe from the Reds on Monday, Jeff Passan of ESPN.com reports.
Lowe had to settle for a minor-league contract with the Reds during that offseason but played his way into a regular role in slashing .266/.341/.480 with 12 home runs over 83 contests. The 31-year-old should be in line for regular reps against right-handed pitching.