White Sox starter Hector Santiago struck out eight batters over 5 1/3 innings Sunday at Houston but suffered the loss.
Santiago (2-5), who has a 3.30 ERA, gave up three earned runs on five hits and four walks. He threw 112 pitches, 69 for strikes.
The 25-year-old has appeared in 18 games and made seven starts for the White Sox. He doesn't regularly get deep into games as a starter but has allowed four runs over his last 11 2/3 innings with 14 Ks. Santiago's next scheduled start is Friday at Kansas City.