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Indians first baseman Carlos Santana returned to the starting lineup and will bat second Thursday night against the White Sox.

Santana has been sidelined since Sunday with back spasms. He has been held without a hit over his last 14 at-bats. He is hitting .220/.365/.341 with four homers and 20 RBI in 35 games plated.

Santana is a .200 (6 for 30) lifetime hitter, with three homers and four RBI against Thursday starter John Danks.

Cleveland is favored (-130) at Chicago, per VegasInsider.com.

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