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Santana will bat leadoff against the Tigers on Friday.

Friday's start is Santana's first atop the batting order in seven major league seasons. Manager Terry Francona flirted with the idea of having Santana lead off during spring training, but Santana has hit almost exclusively out of the five-hole to this point. It's uncertain if this will stick, but what Santana lacks in terms of speed he makes up for with on-base ability.

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