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Santana is not in the lineup for Wednesday's game against the Reds, C. Trent Rosecrans of the Cincinnati Enquirer reports.

The Indians are without the luxury of the DH in an NL park, and manager Terry Francona has decided to go with Mike Napoli over Santana at first base against lefty Brandon Finnegan. Santana is batting .218 so far in May (12-for-55) and the switch-hitter has struggled in a major way against lefties so far this season (.431 OPS).

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