Grube gave up four hits and three earned runs in 1.2 innings on Wednesday for Triple-A Columbus.
Grube finished last season with Columbus, and he will begin 2016 right where he left off. He had a tremendous year in 2015, going 9-0 in 13 starts with a 2.26 ERA in 79.2 innings with the club. The 34-year-old also turned in an impressive spring with the Indians, throwing nine innings without giving up an earned run. Even though he has only pitched in one career game in the majors, Grube has a chance to contribute at some point during the season if he continues to pitch well for Columbus.