White Sox starting pitcher Jose Quintana endured a rough outing as he suffered his second loss of the season Monday night against the Cubs.

Quintana (3-2), who made his 10th start of the season, surrendered a run-scoring single to Alfonso Soriano in the first and a two-run home run to Julio Borbon in the fifth. The left-hander was charged with four runs on four hits and three walks while striking out five in six innings.

Quintana has allowed four runs in two of his last three starts. He is scheduled to make his next start Saturday at Oakland. He is 1-0 with a 3.26 ERA in five starts away from home.