Rockies starting pitcher Juan Nicasio was knocked around as he suffered his second loss of the season Thursday night against the Astros.

Nicasio (4-2) allowed a run-scoring single to J.D. Martinez and Carlos Pena in the sixth inning before getting pulled for Wilton Lopez with two runners on. Lopez surrendered a three-run shot to Chris Carter. Nicasio was charged with five runs on seven hits and three walks while striking out three in five innings of work in a 7-5 defeat.

Nicasio has allowed five runs in two of his last four starts. He is scheduled to make his next start Tuesday at Cincinnati. He is 2-1 with a 4.94 ERA in six starts away from Coors Field.