Castillo was removed from Sunday's game against the Cardinals due to a left hamstring strain, Shannon Drayer of SeattleSports.com reports.
The right-hander had a good chance to pick up a win Sunday as Seattle scored seven runs across the first two frames, but Castillo was lifted due to the hamstring injury after giving up two runs across three innings. The severity of the issue isn't known, and it's unclear if the 31-year-old will be able to make his next turn through the rotation next weekend versus the Rangers.
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