Bermudez will make his first major-league start Wednesday against the Pirates, Stephen Storm of the Marlins Radio Network reports.

Bermudez's first two appearances with the Marlins have come in relief, but 17 of his 20 outings between Double-A Pensacola and Triple-A Jacksonville have been starts. His last start came more than three weeks ago, however, so the lefty will likely be a bit limited in how deep he'll be able to go into Wednesday's contests. Bermudez turned in unremarkable numbers over his six starts with Jacksonville (6.46 ERA, 1.72 WHIP and 28:13 K:BB in 23.2 innings).