Ortiz went 1-for-2 with a solo home run in Wednesday's loss to the Cubs.
Andres Chaparro got the start at first base against southpaw David Peterson, but Ortiz came off the bench in the sixth inning and took Javier Assad deep. It was Ortiz's third homer in nine games since getting called up after the trade deadline, a stretch in which he's batting .292 (7-for-24) with five RBI while handling the strong side of a platoon at first base.