Lyles (1-2) allowed seven runs (six earned) on seven hits and a walk over four innings Monday, striking out two and taking the loss against the Padres.
Most of the damage against Lyles came during a five-run second inning for the Padres before he coughed up a homer to Austin Hedges in the fourth. Over his last four starts, the 29-year-old righty has been hammered for 17 runs in 18.1 innings, raising his season ERA to 7.52. He'll look to get back in the win column in Seattle on Saturday.