Lyles (9-12) allowed five earned runs on eight hits and three walks while striking out three across 3.2 innings, taking the loss against the White Sox on Sunday.
Lyles fired three shutout innings to start the game. However, he fell apart in the fourth inning, allowing five runs while recording just two outs. He allowed a home run to Yasmani Grandal in that inning. The 30-year-old has a 5.36 ERA and 1.44 WHIP with 134 strikeouts in 166.1 innings this season.