Lyles (0-1) was tagged with the loss to the Giants on Saturday when he allowed four runs on three hits and five walks while striking out one in a 7-3 defeat.
Lyles, who made his first start of the season, was unable to consistently locate his pitches. He threw just 42 strikes among his 78 pitches and was particularly off target with his curveball, as just eight of 21 landed in the zone. All four runs allowed originated from runners who reached base via walk. Lyles will look for better results in his next scheduled start, Friday at home against the Angels.