Palacios is out of the lineup for Sunday's game against the Giants.
Though he had started each of the last three matchups with right-handed pitchers, Palacios will give way to Ben Williamson at second base against righty Tyler Mahle. Both Palacios and Williamson are likely headed for reductions in playing time at the keystone with Gavin Lux (shoulder/ankle) drawing closer to a return from the injured list.