Grissom is out of the lineup for Wednesday's game against the Blue Jays.

Grissom had started each of the last three games at second base, going 4-for-11 with a walk, a double, two stolen bases, two RBI and one run. The Red Sox could rotate a number of players at second base down the stretch, including Ceddanne Rafaela. Though Rafaela made each of his last five starts in center field, he may end up seeing more time at the keystone at Grissom's expense now that Tyler O'Neill has been cleared to play the outfield Wednesday after recently being held out of the lineup or limited to designated-hitter duties due to a back issue. Rafaela will join Grissom on the bench Wednesday, however, as Enmanuel Valdez gets the nod at second base.