Lorenzen will start Tuesday's game against the Pirates, Bobby Nightengale of The Cincinnati Enquirer reports.
Lorenzen will start his first game since 2018 as a replacement for Sonny Gray (back), who was placed on the 10-day injured list Sunday. Lorenzen hasn't lasted more than four innings in any of his relief appearances this season, but he should be well-rested since he last pitched Sept. 10.